Tannic acid-rich porcupine bezoars induce apoptosis and cell cycle arrest in human colon cancer cells Peng-Nian Yew, Yau-Yan Lim, Wai-Leng Lee Pharmacognosy Magazine 2019 15(65):523-531 The bezoar is traditionally used in South East Asia and Europe for the treatment of cancer, poisoning, dengue, typhoid, etc. Porcupine bezoar (PB) is a calcified undigested material generally found in porcupine's (Hystrix brachyura) gastrointestinal tract. An initiative of the Center for Biological Diversity. However, limited scientific study has been carried out to verify these traditional claims. Porcupines have an important ecological role and highly developed social structures. A bezoar is a mass found trapped in the gastrointestinal system, though it can occur in other locations. The study quotes one popular website: “The most valuable for the porcupine bezoars are procured from … the rainforest of Indonesia or Borneo. The term has both a modern (medical, scientific) and a traditional usage. The Merck Manual of Diagnosis and Therapy notes that consumption of unripened persimmons has been identified as causing epidemics of intestinal bezoars, and that up to 90% of bezoars that occur from eating too much of the fruit require surgery for removal. Interestingly, the scientific proofs of the usage of bezoar were limited. Bezoars have been used to “treat” everything from fevers to diabetes and even cancer. Porcupine bezoars (PBs) are masses of undigested calcareous concretions formed within the gastrointestinal tract. Please save your money and spare the poor porcupines. This combined method of EP and PBE revealed the process inhibited the proliferation of HeLa cell to 8.48%. In present study, porcupine bezoar was tested to observe its ability in inhibiting cell growth of cancer cell (A549) and its cytotoxicity on Normal Human Gingival Fibroblast Cell (HGF-1). In present study, porcupine bezoar was tested to observe its ability in inhibiting cell growth of cancer cell (A549) and its cytotoxicity on Normal Human Gingival Fibroblast Cell (HGF-1). The porcupine bezoar (PB) used in this study. Thus in this study, porcupine bezoar (PB) was evaluated to explore its ability as a safe anticancer agent. There are several varieties of bezoar, some of which have inorganic constituents and others organic. We found 121 listings (excluding listings advertising supply ability instead of specific bezoars) advertising approximately 680–1332 bezoars and likely representing ten-fold as many porcupines within our three month study period. What Do Porcupines Eat? PB is a mass of indigestible foreign material which could be undigested organic or inorganic material that accumulate and conglomerate in the gastrointestinal tract, most commonly in the stomach. The herb that they seek when sick contains certain chemical compounds that help fight the damages brought by toxins as well as facilitate healing. Antioxidants 2019, 8, 39 3 of 15 2.1. However, to date, medicinal values of porcupine bezoars lack scientific proof. The study quotes one popular website: "The most valuable for the porcupine bezoars are procured from … the rainforest of Indonesia or Borneo. | IEEE Xplore A pseudobezoar is an indigestible object introduced intentionally into the digestive system. A549 cells morphology was observed after treated with bezoars for 72 hours. Porcupine bezoar (PB) was reported to possess medicinal properties in old medical manuscript. Yes, eating the (real) porcupine dates can help our body to fight and cure a lot of illness. IEEE Xplore, delivering full text access to the world's highest quality technical literature in engineering and technology. Porcupine Bezoar Medical Value According to Chinese medicine records, our ancestors and some aborigines have knowledge on the medicinal values of the porcupine bezoar. Porcupine Bezoar stone is a type of globular stone-like mass occasionally Produced in a porcupine’s internal body. Based on the weight of the powders, and the assumption that they might have contained other ingredients, the researchers estimate this translated to at least 680 and as many as 1,300 bezoars. It was just over a year ago that President Trump announced, “The golden era of American energy is now underway,” saying that his policies focused on exploiting oil, … Value causing the bezoars … in this study … additionally, porcupine bezoar ( PB is! Crushed consists of a porcupine ’ s diet is wide, varied, and little! Is used as anti-inflammation, antioxidant, natural anti body, immunization booster and body-detox morphology was observed after with. 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